CHINJ membership is home to state-of-the-art research resources that enable scientists to understand the detailed cellular and molecular mechanisms of childhood diseases.
CHINJ houses several advanced imaging systems enabling sophisticated analysis of fixed cells, and live cell and in vivo imaging that support all CHINJ investigators, including:
CHINJ has advanced single cell sorting and analysis instruments supporting research across a range of immunologic and neuroscience research, including:
Directed by Zhiping Pang, MD, PhD CHINJ researchers derive and functionally analyze different human neuronal subtypes using cellular imaging and electrophysiology approaches, as well studying a variety of neuronal culture systems including single neuron, mixed neuronal/glial cell, and human cerebral organoid cultures.
Directed by M. Chiara Manzini, PhD, CHINJ researchers perform basic neurobehavioral analyses in mouse models of human neurodevelopmental disorders to correlate genetic alterations with behavioral phenotypes.
CHINJ investigators may access Rutgers University shared resources including:
Directed by Drs. Peter Romenienko and Ghassan Yehia, this resource of Rutgers Cancer Institute of New Jersey is physically located at CHINJ and provides expertise and assistance in development and production of genetically modified mouse models of human disease.
This resource is used by CHINJ investigators to model human neurodevelopmental and childhood musculoskeletal disorders in the zebrafish model system, and to rapidly screen potential novel therapeutics.
CHINJ scientists utilize the clinical research cores of the New Jersey Alliance for Clinical and Translational Science (NJ ACTS) to perform research translating laboratory discovery into clinical practice.